THE HAEMATOLOGICAL CHANGES OBSERVED IN DOGS INFESTED WITH SARCOPTES SCABIE VAR. CANIS AND TREATED WITH IVERMECTIN, CYPERMETHRIN, CITRUS AND NEEM SEED OIL

Abstract

The haematological changes associated with anti-parasitic effects of Ivermectin, Cypermethrin, Citrus oil, Neem seed oil in Sarcoptes infested dogs is scanty in literature. Thus, this study evaluates the safety of these therapeutic interventions using changes in haematological indices. Thirty dogs were enrolled for the study out of which twenty five were infested with sarcoptes mites and the other five were sarcoptes free. Botanical preparations were made and oils were extracted for use. Infested dogs were grouped in fives and were treated with Ivermectin, Cypermethrin, Citrus oil, Neem seed oil, and Petroleum jelly (Vehicle) as recommended for six weeks. The PCV, HB, RBC, WBC, platelets, lymphocytes, neutrophils, monocytes, eosinophils, and platelet lymphocyte ratios were evaluated following various treatments. Neem seed oil and Cypermethrin pour-on significantly (p < 0.05) improved the PCV, Hb and RBC of infested dogs. Citrus treated dogs had significantly (p < 0.05) lower WBC and platelet counts. PLR was observed to be lowest in Cypermethrin treated dogs when compared with other various treatment. Treatment of canine scabies with these therapeutic mediations did not cause serious haematological derangements hence the use of any of the botanical/systemic therapy were safe to use in dogs.

Keywords: Acaricides, Haematology, Sarcoptes scabiei, Dogs, Botanical, Systemic